Circadin
£18.50
Circadin is an effective treatment to help manage jet lag in adults aged 18 years and over, following a clinical assessment.
It works by supplementing melatonin, a natural hormone that regulates the sleep-wake cycle, helping your body, improving sleep quality after travel.
Please Note: You are also required to complete a form at checkout. In addition, a video consultation with our pharmacist may be required.
Categories: Age verification, Jet Lag, Online Clinic, Travel Health
Tags: PGD
What is Circadin 2mg Modified-Release Tablets used for?
Circadin 2mg Modified-Release Tablets contain the active substance melatonin, which belongs to a natural group of hormones produced by the body that help regulate the sleep-wake cycle.
Circadin is supplied for the short-term management of jet lag in adults. Jet lag can occur after travelling across multiple time zones and may cause difficulty falling asleep, disturbed sleep, daytime fatigue and reduced alertness.
How Circadin works
Melatonin helps regulate the body’s internal clock (circadian rhythm), which can become disrupted when travelling across time zones. Circadin is a modified-release formulation, designed to release melatonin gradually to mimic the body’s natural overnight production.
By helping to reset the sleep-wake cycle to the new time zone, Circadin supports improved sleep quality and helps reduce the symptoms associated with jet lag.
Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure how to use this medicine.
The recommended dose for adults:
Take one tablet 30–60 minutes before bedtime for up to 5 days.
Take after food, swallow whole with water and do not crush or chew the tablet.
If you take more Circadin than you should
If you have accidentally taken too much of your medicine, contact your doctor or pharmacist as soon as possible. Taking more than the recommended daily dose may make you feel drowsy.
If you forget to take Circadin
If you forget to take your tablet, take another as soon as you remember, before going to sleep, or wait until it is time to take your next dose, then go on as before. Do not take a double dose to make up for a forgotten dose.
If you stop taking Circadin
There are no known harmful effects if treatment is interrupted or ended early. The use of Circadin is not known to cause any withdrawal effects after treatment completion.
Like all medicines, this medicine can cause side effects, although not everybody gets them. Some of the side effects are temporary with continued treatment or disappeared when treatment is stopped.
Side effects are rare when taken for short term relief of jet lag.
Side Effects
Uncommon
Irritability, nervousness, restlessness, insomnia, abnormal dreams, nightmares, anxiety, migraine, headache, lethargy, restlessness associated with increased activity, dizziness, tiredness, high blood pressure, upper abdominal pain, indigestion, mouth ulceration, dry mouth, nausea, changes in the composition of your blood which could cause yellowing of the skin or eyes, inflammation of the skin, night sweats, itching, rash, dry skin, pain in extremities, menopausal symptoms, feeling of weakness, excretion of glucose in the urine, excess proteins in the urine, abnormal liver function and weight increase
Rare
Shingles, high level of fatty molecules in the blood, low serum calcium levels in the blood, low sodium levels in the blood, altered mood, aggression, agitation, crying, stress symptoms, early morning awakening, increased sex drive, depressed mood, memory impairment, disturbance in attention, dreamy state, restless legs syndrome, poor quality sleep, ‘pins and needles’ feeling, watery eyes, dizziness when standing or sitting, hot flushes, acid reflux, stomach disorder, blistering in the mouth, tongue ulceration, stomach upset, vomiting, abnormal bowel sounds, wind, excess saliva production, bad breath, abdominal discomfort, gastric disorder, inflammation of the stomach lining, eczema, skin rash, hand dermatitis, itchy rash, nail disorder, arthritis, muscle spasms, neck pain, night cramps, prolonged erection that might be painful, inflammation of the prostate gland, tiredness, pain, thirst, passing large volumes of urine, urinating during the night, increased liver enzymes, abnormal blood electrolytes and abnormal laboratory tests.
Frequency not known
- Hypersensitivity reaction
- Swelling of mouth or tongue
- Swelling of the skin
- Abnormal milk secretion
Serious Side Effects
If you experience any of the following serious side effects, stop taking the medicine and contact your doctor immediately:
Uncommon
- Chest pain
Rare
- Loss of consciousness or fainting
- Severe chest pain due to angina
- Feeling your heartbeat
- Depression
- Visual impairment
- Blurred vision
- Disorientation
- Vertigo (a feeling of dizziness or “spinning”)
- Presence of red blood cells in the urine
- Reduced number of white blood cells in the blood
- Reduced blood platelets, which increases risk of bleeding or bruising
- Psoriasis
Warning & Precautions
Talk to your doctor or pharmacist before taking Circadin.
- If you suffer from liver or kidney problems. No studies on the use of Circadin in people with liver or kidney diseases have been performed, you should speak to your doctor before taking Circadin as its use is not recommended.
- If you have been told by your doctor that you have an intolerance to some sugars.
- If you have been told you suffer from an autoimmune disease (where the body is ‘attacked’ by its own immune system). No studies on the use of Circadin in people with auto-immune diseases have been performed; therefore, you should speak to your doctor before taking Circadin as its use is not recommended.
- Circadin can make you feel drowsy, you should be careful if the drowsiness affects you as it may impair your ability on tasks such as driving.
- Smoking may make Circadin less effective, because the components of tobacco smoke can increase the breakdown of melatonin by ithe liver.
Age Restrictions
Adults over the age of 18 years old
Other Medicines and Conditions
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. These medicines include:
- Fluvoxamine (used for the treatment of depression and obsessive compulsive disorder), psoralens (used in the treatment of skin disorders e.g. psoriasis), cimetidine (used in the treatment of stomach problems such as ulcers), quinolones and rifampicin (used in the treatment of bacterial infections), oestrogens (used in contraceptives or hormone replacement therapy) and carbamazepine (used in the treatment of epilepsy).
- Adrenergic agonists/antagonists (such as certain types of medicines used to control blood pressure by constricting blood vessels, nasal decongestants, blood pressure lowering medicines), opiate agonists/antagonists (such as medicinal products used in the treatment of drug addiction), prostaglandin inhibitors (such as nonsteroidal anti-inflammatory medicines), antidepressant medication, tryptophan and alcohol.
- Benzodiazepines and non-benzodiazepine hypnotics (medicines used to induce sleep such as zaleplon, zolpidem and zopiclone)
- Thioridazine (for the treatment of schizophrenia) and imipramine (for the treatment of depression).
Circadin with food, drink and alcohol
Take Circadin after you have eaten. Do not drink alcohol before, during or after taking Circadin, because it reduces the effectiveness of Circadin.
Driving and using machines
Circadin may cause drowsiness. If you are affected, you should not drive or operate machinery. If you suffer from continued drowsiness, then you should consult your doctor.
Pregnancy and Breastfeeding
This medicine is not suitable for use in pregnancy and breastfeeding.
Patient Information Leaflet
https://www.medicines.org.uk/emc/files/pil.2809.pdf
Ingredients
- Active Ingredients: 2mg Melatonin
- Other Ingredients: ammonio methacrylate copolymer type B, calcium hydrogen phosphate dihydrate, lactose monohydrate, silica (colloidal anhydrous), talc and magnesium stearate
Product Information
- Brand Name: Circadin
- Route of Administration: Oral
- Legal Classification: Prescription Only Medication (POM)
- Strength: 2mg
- Dosage From: Tablet
Storage
- Keep this medicine out of the sight and reach of children.
- Do not use this medicine after the expiry date which is stated on the carton (EXP). The expiry date refers to the last day of that month.
- Do not store above 25°C. Store in the original package in order to protect from light.
- Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help to protect the environment.
Advice & Helpful Links
