Disprin Aspirin Soluble Tablets 300mg – 32 Tablets

Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist have told you. Check with your doctor or pharmacist if you are not sure. Use for shortest possible time, if symptoms persist for more than 3 days, seek advice from a healthcare professional.

Adults, the elderly, children over 16:

Take 2 to 3 tablets, dissolve the tablets in water before taking.

Repeat the dose every 4-6 hours if needed, but do not exceed 12 tablets in 24 hours. Do not exceed the stated dose.

If symptoms persist consult your doctor.

If you take more Disprin than you should

If you start feeling sick or experience symptoms such as deafness, ringing in your ears, dizziness, abnormal sweating, warm hand and feet with racing pulse, an increased breathing rate, dehydration, you should seek immediate medical advice.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Side effects

• Indigestion
• Upset stomach

Serious side effects

• Blood disorders such as hypoprothrombiaemia, thrombocytopenia (reduction in blood platelets which might mean that you bleed or bruise more easily), aplastic anaemia resulting in pancytopenia (reduction in white and red blood cells), agranulocytosis (reduction in white blood cells which makes infection more likely).
• Fever
• Itchy skin rash caused by allergic reaction, including swelling (e.g. hives)
• More rarely, severe skin reactions may occur such as rash, peeling, flaking, blistering of the skin (e.g. Stevens-Johnson syndrome)
• Fluid retention causing swelling
• Signs of aseptic meningitis with neck stiffness, headache, feeling sick, being sick or fever
• Swelling (oedema), high blood pressure, heart failure or attack
• Asthma or bronchospasm (narrowing of the airways that causes wheezing or difficulty breathing), shortness of breath
• Stomach or intestinal ulcers, sometimes with bleeding and perforation, black tarry stools, vomiting blood
• Liver problems
• Gout (high levels of uric acid in the blood)

Caution should be implemented in patients with a history of other bleeding events such as intercranial haemorrhage, due to the increased risk of intercranial haemorrhage with acetylsalicylic acid use.

Overuse headaches: use of NSAIDs for 15 or more days per month, for 3 months or more, increases your risk of medication overuse.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

Warnings and Precautions

Disprin contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium free’.

Disprin contains soy protein. If you are allergic to peanut or soya, do not use this medicinal product

Age Restrictions

Aspirin should not be given to children aged under 16 years, unless on the advice of a doctor.

There is a possible association between aspirin and Reye’s syndrome when given to children. Reye’s syndrome is a very rare disease, which can be fatal.

Other Medicines & Conditions

Always speak to a pharmacist or doctor before taking aspirin with another medicine.

Do not take Disprin if you:

• Are allergic to aspirin or to any of the excipients
• Are allergic to other NSAIDs
• Have nasal polyps associated with asthma
• Have a history of gastrointestinal bleeding or perforation when previously taking NSAIDs
• Have or have had peptic ulceration or blood disorders including haemophilia
• Suffer from liver, kidney or heart problems
• Are a child under 16 years due to a possible risk of Reye’s Syndrome, unless specifically indicated
• Are allergic to peanut or soya. This product contains soy protein.

Other medicines and Disprin

• To reduce the chance of side effects, do not take this product with other NSAID containing products. If you are on low dose aspirin (up to 75 mg daily), speak to your doctor or pharmacist before you take this medicine.

Avoid taking this product with corticosteroid tablets, quinolone antibiotics or drugs that are prescribed:

• To thin your blood or prevant clotting (e.g. warfarin)
• For depression (e.g. SSRIs)
• To timulate your heart (e.g. glycosides)
• Medicines to treat high blood pressure (e.g. ACE inhibitors and calcium channel blockers)
• For the temporary suppression of your immune system (e.g. methotrexate, ciclosporin, tacrolimus)
• For HIV treatment (e.g. zidovudine)
• As anti-sickness treatments (e.g. metoclopromide and domperidone)
• As treatments for epilepsy (e.g. valproate)
• As treatments for gout (hyperuricemia)
• For pregnancy termination (e.g. mifepristone)
• Metamizole (substance to decrease pain and fever) may reduce the effect of acetylsalicylic acid on platelet aggregation (blood cells sticking together and forming a blood clot), when taken concomitantly. Therefore, this combination should be used with caution in patients taking low dose aspirin for cardioprotection.

Pregnancy and Breastfeeding

Not recommended for use in Pregnancy and Breastfeeding.

Patient Information Leaflet

https://www.medicines.org.uk/emc/files/pil.614.pdf

Ingredients

• Active Ingredients: Each dispersible tablet contains 300mg of aspirin.
• Other Ingredients: Calcium carbonate, maize starch, citric acid, talc, sodium lauryl sulphate, saccharin, crospovidone and lime flavour.

Product Information

• Brand Name: Disprin
• Route of Administration: Oral
• Legal Classification: P
• Strength: 300mg
• Dosage Form: Soluble tablet

Storage

• Store below 25°C in a dry place.
• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.
• Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

Additional & Helpful links

https://www.nhs.uk/live-well/pain/